Benign Myoclonic Epilepsy in Infancy - Revision history

EEGpedia at 21:52, 8 June 2018

2018-06-08T21:52:51Z

EEGpedia at 21:52, 8 June 2018

2018-06-08T21:52:23Z

EEGpedia at 21:51, 8 June 2018

2018-06-08T21:51:52Z

EEGpedia at 15:46, 8 June 2018

2018-06-08T15:46:16Z

EEGpedia at 15:44, 8 June 2018

2018-06-08T15:44:23Z

EEGpedia: Created page with "==Background== * One of the idiopathic generalized epilepsies * 1% to 2% of epilepsies that start before the age of 3 years * Seizures start between 0.5 and 3 years of age in..."

2018-06-08T15:32:51Z

Created page with "==Background== * One of the idiopathic generalized epilepsies * 1% to 2% of epilepsies that start before the age of 3 years * Seizures start between 0.5 and 3 years of age in..."

New page

==Background==
* One of the idiopathic generalized epilepsies
* 1% to 2% of epilepsies that start before the age of 3 years
* Seizures start between 0.5 and 3 years of age in developmentally normal children. However, some cases have a later onset up to 4 years
* A family history of febrile seizures and epilepsy is often reported
* Remission usually occurs within 1 year (6 months to 5 years) from onset.
* The outcome is generally benign. In rare cases, myoclonic epilepsy such as [[Juvenile Myoclonic Epilepsy]] may follow Benign Myoclonic Epilepsy in Infancy

==Clinic==
* Myoclonic jerks involving mostly the upper part of the body, singular or clusters
* Consciousness is normally intact
* Photosensitivity in 20% of the patients
* Unexpected acoustic or tactile stimuli can elicit a the myoclonic jerks in 10%.

==Treatment==
* valproic acid was effective in 23 of 30 treated patients <ref>Auvin, S. , Pandit, F. , De Bellecize, J. , Badinand, N. , Isnard, H. , Motte, J. , Villeneuve, N. , Lamblin, M. , Vallée, L. and , (2006), Benign Myoclonic Epilepsy in Infants: Electroclinical Features and Long‐term Follow‐up of 34 Patients. Epilepsia, 47: 387-393. doi:10.1111/j.1528-1167.2006.00433.x</ref>
* Patients with acoustic and somatosensory evoked myoclonic seizures may not need treatment.

==EEG==
* '''Inter-ictal''': Sometimes generalized [[Spike slow wave complex]] or [[Polyspikes slow wave complex]]
* '''Ictal''': Brief generalized [[Spike slow wave complex]] or [[Polyspikes slow wave complex]]
* During sleep in most of the patients the myoclonic seizures persists
* Sometimes photosensitivity
* Normal background rhythm
* Electromyogram show one or repetitive myoclonia

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'''''Generalized (poly)spike slow wave in a 15 year old male with JME (source) '''''
[[File:Juvenile_myoclonic_epilepsy_in_a_15_year_old_male_(source)_EEGpedia.png|border|none|1200px|left]]

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'''Notes'''
<references/>

@@ Line 14: / Line 14: @@
 ==Treatment==
-* valproic acid was effective in 23 of 30 treated patients <ref>Auvin, S. , Pandit, F. , De Bellecize et al, Benign Myoclonic Epilepsy in Infants: Electroclinical Features and Long‐term Follow‐up of 34 Patients. Epilepsia, 2006 47: 387-393. doi:10.1111/j.1528-1167.2006.00433.x</ref>
+* Valproic acid was effective in 23 of 30 treated patients <ref>Auvin, S. , Pandit, F. , De Bellecize et al, Benign Myoclonic Epilepsy in Infants: Electroclinical Features and Long‐term Follow‐up of 34 Patients. Epilepsia, 2006 47: 387-393. doi:10.1111/j.1528-1167.2006.00433.x</ref>
 * Patients with acoustic and somatosensory evoked myoclonic seizures may not need treatment.

@@ Line 27: / Line 27: @@
 ----
-'''''Generalized (poly)spike slow wave in a 15 year old male with JME (source) '''''
+'''''5 year old girl with 3 Hz generelized polyspike waves and myoclonic jerks (double banana and EMG on deltoid muscle)'''''
-[[File:Juvenile_myoclonic_epilepsy_in_a_15_year_old_male_(source)_EEGpedia.png|border|none|1200px|left]]
+[[File:5_year_old_girl_with_3_Hz_generelized_polyspike_waves_and_myoclonic_jerks_(double_banana_and_EMG_on_deltoid_muscle)_EEGpedia.png|border|none|1200px|left]]

@@ Line 12: / Line 12: @@
 * Photosensitivity in 20% of the patients
 * Unexpected acoustic or tactile stimuli can elicit a the myoclonic jerks in 10%.
 ==Treatment==
@@ Line 20: / Line 21: @@
 * '''Inter-ictal''': Usually normal, sometimes generalized [[Spike slow wave complex]] or [[Polyspikes slow wave complex]]
 * '''Ictal''': Brief generalized [[Spike slow wave complex]] or [[Polyspikes slow wave complex]]
 * Sometimes photosensitivity
 * Normal background rhythm

@@ Line 18: / Line 18: @@
 ==EEG==
-* '''Inter-ictal''': Sometimes generalized [[Spike slow wave complex]] or [[Polyspikes slow wave complex]]
+* '''Inter-ictal''': Usually normal, sometimes generalized [[Spike slow wave complex]] or [[Polyspikes slow wave complex]]
 * '''Ictal''': Brief generalized [[Spike slow wave complex]] or [[Polyspikes slow wave complex]]
 * During sleep in most of the patients the myoclonic seizures persists